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HAVCR2靶点

HAVCR2(Gene ID:84868),也被称为TIM-3(T细胞免疫球蛋白和粘蛋白结构域包含蛋白3),是一种编码主要在免疫细胞上表达的细胞表面蛋白的基因。TIM-3在调节免疫反应中起着关键作用,并与各种免疫相关疾病有关。TIM-3最初是作为T细胞表面的标记物被发现的,后来发现它在其他免疫细胞类型上也有表达,包括树突细胞和自然杀伤细胞。由于其在在T细胞衰竭和免疫耐受的背景下在免疫检查点信号传导中的作用它获得了极大的关注。TIM-3是一种免疫检查点受体,在调节T细胞反应中起着关键作用。它与其配体如半乳糖凝集素-9和磷脂酰丝氨酸(PtdSer)相互作用,传递抑制信号。T细胞上的TIM-3参与导致T细胞衰竭的过程,抑制它们的效应子功能。TIM-3与慢性感染(例如,HIV和肝炎)、癌症和自身免疫性疾病中的T细胞功能障碍和衰竭有关。在这些情况下,它对T细胞的上调导致免疫反应受损。TIM-3已经成为癌症免疫治疗的靶点。阻断TIM-3相互作用的抗体可以通过防止T细胞衰竭和促进细胞毒性T细胞活性来增强抗肿瘤免疫反应。TIM-3与多发性硬化症和类风湿性关节炎等自身免疫性疾病有关。TIM-3信号的失调会导致不受控制的免疫激活。

卡梅德生物是一家专注于生物技术领域的创新公司,致力于为科研机构、高校和公司提供高质量的HAVCR2蛋白、HAVCR2抗体等高质量的靶点产品。卡梅德生物始终秉承着客户至上的原则,致力于为科研机构、高校和公司提供最优质的HAVCR2相关产品,推动生物技术领域的不断创新和发展。

 

卡梅德推出的特色靶点HAVCR2蛋白产品:

 

编号

产品名称

物种

宿主

规格

询价

KMPH1552

Human HAVCR2/TIM3 Protein, Fc & His Tag

Human

HEK293 Cells

50ug, 100ug

询价

KMPH1553

Human HAVCR2/TIM3 Protein, His Tag

Human

HEK293 Cells

50ug, 100ug

询价

MOP1874

Mouse HAVCR2/TIM3 Protein, Fc Tag

Mouse

HEK293 Cells

50ug, 100ug

询价

MOP1875

Mouse HAVCR2/TIM3 Protein, His Tag

Mouse

HEK293 Cells

50ug, 100ug

询价

KMPH5907

Human HAVCR2/TIM3 Protein, Fc Tag

Human

HEK293 Cells

50ug, 100ug

询价

KMPH5908

Human HAVCR2/TIM3 Protein, Fc & His Tag

Human

HEK293 Cells

50ug, 100ug

询价

KMPH5909

Human HAVCR2/TIM3 Protein, Fc Tag

Human

HEK293 Cells

50ug, 100ug

询价

KMPH5910

Human HAVCR2/TIM3 Protein, Strep Tag

Human

HEK293 Cells

50ug, 100ug

询价

KMPH5911

Human HAVCR2/TIM3 Protein, Fc & His Tag

Human

HEK293 Cells

50ug, 100ug

询价

KMPH5912

Human HAVCR2/TIM3 Protein, Fc Tag

Human

HEK293 Cells

50ug, 100ug

询价

KMPH6035

Human HAVCR2/TIM3 Protein, Fc Tag

Human

HEK293 Cells

50ug, 100ug

询价

KMH513

Recombinant Human HAVCR2 Protein, His Tag

Human

Mammalian cells

50ug, 100ug

询价

MOP2174

Recombinant Mouse Havcr2/Tim-3 Protein, His Tag

Mouse

Mammalian cells

50ug, 100ug

询价

MOP2294

Recombinant Mouse TIM-3/Havcr2 Protein, His Tag

Mouse

Mammalian cells

50ug, 100ug

询价

KMH1807

Recombinant Human TIM-3/HAVCR2 C-fc Protein, Fc & His Tag

Human

Mammalian cells

50ug, 100ug

询价

MOP2295

Recombinant Mouse TIM-3/Havcr2 C-fc Protein, Fc Tag

Mouse

Mammalian cells

50ug, 100ug

询价

KMH1808

Recombinant Human TIM-3/HAVCR2 Protein, His Tag

Human

Mammalian cells

50ug, 100ug

询价

MOP2296

Recombinant Mouse TIM-3/Havcr2 Protein, His Tag

Mouse

Mammalian cells

50ug, 100ug

询价

KMP2288

Human HAVCR2 Protein, mFc Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2301

Human HAVCR2 Protein, Fc Tag, Avi Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2310

Cynomolgus HAVCR2 Protein, Fc Tag

Cynomolgus

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2336

Mouse HAVCR2 Protein, Fc Tag

Mouse

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2340

Mouse HAVCR2 Protein, His Tag

Mouse

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2352

Marmoset HAVCR2 Protein, His Tag

Marmoset

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2354

Mouse HAVCR2 Protein, His Tag

Mouse

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2382

Human HAVCR2 Protein, Fc Tag, His Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2399

Cynomolgus HAVCR2 Protein, His Tag

Cynomolgus

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2404

Human HAVCR2 Protein, His Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

询价

 

卡梅德推出的特色靶点HAVCR2抗体产品:

 

编号

产品名称

物种

宿主

应用

规格

询价

PA7062

Rabbit Anti-Human HAVCR2 pAb

Human

Rabbit

WB, IF

50ul, 100ul

询价

PA7063

Rabbit Anti-Human HAVCR2 pAb

Human

Rabbit

IHC, IF

50ul, 100ul

询价

PA7064

Rabbit Anti-Human HAVCR2 pAb

Human

Rabbit

WB, IHC

50ul, 100ul

询价

PA10794

Rabbit Anti-Human HAVCR2 pAb

Human

Rabbit

WB

50ul, 100ul

询价

PA12960

Rabbit Anti-Human HAVCR2 pAb

Human

Rabbit

WB, IHC

50ul, 100ul

询价

PAV1688

Rabbit Anti-HAVR2/HAVCR2 Polyclonal Antibody

WB, ELISA

Rabbit

WB, ELISA

100ul

询价

 

卡梅德其他优势产品:

 

重组蛋白

病毒蛋白

细菌蛋白