服务热线
400-621-6806

周一至周六

8:00-18:00

在线客服
销售支持二维码
 

技术资源

文档下载

联系我们

服务电话:400-621-6806

地址:天津市武清区国际企业社区A5号楼四层,301700

邮箱:info@kmdbioscience.com

在线留言

  •   
  •   
  •   
  • 看不清
CD86/B7-2靶点

CD86(Gene ID:942),也被称为B7-2,是由CD86基因编码的细胞表面蛋白。它是免疫检查点分子B7家族的成员,在调节免疫反应中起关键作用。CD86在20世纪90年代早期被鉴定为在树突细胞、巨噬细胞和B细胞等抗原呈递细胞(APCs)上表达的共刺激分子,它与T细胞上的受体CD28和CTLA-4 (CD152)相互作用,调节T细胞活化和分化。CD86是一种关键的共刺激分子,与T细胞上的CD28相互作用。除了T细胞受体(TCR)信号,这种相互作用在T细胞活化过程中提供了至关重要的第二信号。CD86与CD28的结合增强了T细胞增殖、细胞因子产生和效应子功能,确保了有效的免疫反应。CD86也在免疫耐受中发挥作用。当T细胞遇到表达CD86但没有充分TCR激活的APCs时,会导致无反应性(无反应状态)或调节性T细胞(Treg)诱导。这些机制有助于防止对自身抗原的不必要的免疫反应。CD86在免疫调节中具有双重作用。虽然它通过CD28提供共刺激,但它也可以与活化T细胞上的抑制性受体CTLA-4 (CD152)相互作用。CTLA-4与CD28竞争结合CD86,抑制T细胞活化,有助于免疫稳态。CD86在T细胞共刺激、免疫耐受、免疫检查点调节中的关键作用及其作为治疗靶点的潜力突出了其在免疫应答和临床应用中的重要性。

卡梅德生物是一家专注于生物技术领域的创新公司,致力于为科研机构、高校和公司提供高质量的CD86/B7-2蛋白、CD86/B7-2抗体等高质量的靶点产品。卡梅德生物始终秉承着客户至上的原则,致力于为科研机构、高校和公司提供最优质的CD86/B7-2相关产品,推动生物技术领域的不断创新和发展。

 

卡梅德推出的特色靶点CD86/B7-2蛋白产品:

 

编号

产品名称

物种

宿主

规格

询价

KMPH2279

Human CD86 Protein, Fc & His Tag

Human

HEK293 Cells

100ug, 200ug

询价

KMPH2280

Human CD86 Protein, His Tag

Human

HEK293 Cells

100ug, 200ug

询价

MOP1089

Mouse CD86 Protein, His & Fc Tag

Mouse

HEK293 Cells

100ug, 200ug

询价

MOP1090

Mouse CD86 Protein, His Tag

Mouse

HEK293 Cells

100ug, 200ug

询价

PR175

Rat CD86 Protein, His Tag

Rat

HEK293 Cells

100ug, 200ug

询价

PM306

Cynomolgus CD86 Protein, Fc Tag

Cynomolgus

HEK293 Cells

100ug, 200ug

询价

PM307

Cynomolgus CD86 Protein, His Tag

Cynomolgus

HEK293 Cells

100ug, 200ug

询价

KMPH5804

Human CD86 Protein, Fc & His Tag

Human

HEK293 Cells

100ug, 200ug

询价

KMPH5805

Human CD86 Protein, Fc & His Tag

Human

HEK293 Cells

100ug, 200ug

询价

KMPH5806

Human CD86 Protein, Fc & His Tag

Human

HEK293 Cells

100ug, 200ug

询价

KMPH5807

Human CD86 Protein, Fc & His Tag

Human

HEK293 Cells

100ug, 200ug

询价

KMPH5808

Human CD86 Protein, Fc & His Tag

Human

HEK293 Cells

100ug, 200ug

询价

KMPH5809

Human CD86 Protein, Fc & His Tag

Human

HEK293 Cells

100ug, 200ug

询价

KMH261

Recombinant Human CD86 Protein, His Tag

Human

Mammalian cells

50ug, 100ug

询价

MOP2073

Recombinant Mouse B7-2/Cd86 Protein, Fc Tag

Mouse

Mammalian cells

50ug, 100ug

询价

MOP2074

Recombinant Mouse B7-2/Cd86 Protein, His Tag

Mouse

Mammalian cells

50ug, 100ug

询价

PO125

Recombinant Rabbit B7-2/CD86 Protein, His Tag

Rabbit

Mammalian cells

50ug, 100ug

询价

PO126

Recombinant Rat B7-2/Cd86 Protein, His Tag

Rat

Mammalian cells

50ug, 100ug

询价

KMP2708

Human CD86 Protein, hFc Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2709

Human CD86 Protein, His Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2710

Human CD86 Protein, His Tag, Avi Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2295

Mouse CD86 Protein, His Tag

Mouse

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2296

Rat CD86 Protein, His Tag

Rat

HEK293 Cells

50ug, 100ug, 200ug

询价

 

卡梅德推出的特色靶点CD86/B7-2抗体产品:

 

编号

产品名称

物种

宿主

应用

规格

询价

PM1014

Cluster of differentiation 86

Human , Mouse , Rat , Dog , Pig , Cow , Sheep

Rabbits

WB , IHC-P , ICC/IF , FC

100ul

询价

PA5715

Rabbit Anti-Human CD86 pAb

Human

Rabbit

WB, IHC, IF

50ul, 100ul

询价

PA10495

Rabbit Anti-Human CD86 pAb

Human

Rabbit

WB, IF, IP

50ul, 100ul

询价

PA12913

Rabbit Anti-Human CD86 pAb

Human

Rabbit

WB, IHC

50ul, 100ul

询价

MA509

Rabbit Anti-Human CD86 mAb

Human

Rabbit

WB

50ul, 100ul

询价

 

卡梅德其他优势产品:

 

重组蛋白

病毒蛋白

细菌蛋白