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CD3E靶点

CD3E基因(Gene ID:916)是CD3复合物的一部分,该复合物由CD3E、CD3D和CD3Z(也分别称为CD3-γ、δ和ζ)组成。这些蛋白质与TCR相关,对T细胞功能至关重要。特别地,CD3E还充当CD3复合物的ε链。CD3E参与胸腺中T细胞的发育,它在T细胞前体中早期表达,并在TCR复合物的装配和表面表达中起作用。没有功能性CD3E,正常的T细胞发育就会受损。CD3E对于T细胞识别抗原是必不可少的。它与CD3D和CD3Z形成复合物,与TCRα和β链一起形成完整的TCR复合物。这种复合物与抗原呈递细胞(APCs)上主要组织相容性复合物(MHC)分子呈递的抗原肽结合。CD3E是免疫治疗的靶点,特别是在双特异性抗体(BsAbs)和嵌合抗原受体(CAR) T细胞疗法的开发中。与CD3E和肿瘤特异性抗原结合的BsAbs重新引导T细胞攻击癌细胞,而用CD3E特异性受体改造的CAR T细胞在癌症治疗中显示出广泛的应用前景。

卡梅德生物是一家专注于生物技术领域的创新公司,致力于为科研机构、高校和公司提供高质量的CD3E蛋白、CD3E抗体等高质量的靶点产品。卡梅德生物始终秉承着客户至上的原则,致力于为科研机构、高校和公司提供最优质的CD3E相关产品,推动生物技术领域的不断创新和发展。

 

卡梅德推出的特色靶点CD3E蛋白产品:

 

编号

产品名称

物种

宿主

规格

询价

KMPH2475

Human CD3E Protein, Fc & His Tag

Human

HEK293 Cells

20ug, 50ug

询价

KMPH2476

Human CD3E Protein, His Tag

Human

HEK293 Cells

20ug, 50ug

询价

PM193

Rhesus CD3E Protein, Fc Tag

Rhesus

HEK293 Cells

20ug, 50ug

询价

PM194

Rhesus CD3E Protein, His Tag

Rhesus

HEK293 Cells

20ug, 50ug

询价

MOP1967

Mouse CD3D & CD3E Protein

Mouse

HEK293 Cells

 

询价

KMPH5772

Human CD3D & CD3E Protein

Human

HEK293 Cells

 

询价

MOP1968

Mouse CD3D & CD3E Protein

Mouse

HEK293 Cells

 

询价

KMPH5777

Human CD3D & CD3E Protein

Human

HEK293 Cells

 

询价

KMPH5780

Human CD3E & CD3G Protein, His & Fc Tag

Human

HEK293 Cells

20ug, 50ug

询价

MOP1971

Mouse CD3E & CD3G Protein, Fc Tag

Mouse

HEK293 Cells

20ug, 100ug

询价

PM142

Cynomolgus Monkey CD3D & CD3E Protein

Cynomolgus Monkey

 

 

询价

KMPH6059

Human CD3E Protein, Fc & His Tag

Human

HEK293 Cells

20ug, 50ug

询价

KMPH6065

Human CD3E Protein, Fc & His Tag

Human

HEK293 Cells

20ug, 50ug

询价

KMPH6187

Human CD3E Protein, Strep Tag

Human

HEK293 Cells

20ug, 50ug

询价

KMPH6231

Human CD3E Protein, Fc & His Tag

Human

HEK293 Cells

20ug, 50ug

询价

KMPH6239

Human CD3D & CD3E Protein

Human

 

 

询价

KMPH6241

Human CD3E Protein, Fc Tag

Human

HEK293 Cells

20ug, 50ug

询价

KMPH6261

Human CD3D & CD3E Protein

Human

 

 

询价

KMPH6278

Human CD3D & CD3E Protein

Human

 

 

询价

KMPH6282

Human CD3E Protein, Fc & His Tag

Human

HEK293 Cells

20ug, 50ug

询价

KMH152

Recombinant Human CD3E Protein, His Tag

Human

Mammalian cells

50ug, 100ug

询价

KMP2811

Human CD3e Protein, hFc Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

询价

KMP2812

Human CD3e Protein, His Tag

Human

CHO Cells

50ug, 100ug, 200ug

询价

KMP3539

Human CD3D & CD3E Heterodimer Protein, His Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

询价

 

卡梅德推出的特色靶点CD3E抗体产品:

 

编号

产品名称

物种

宿主

应用

规格

询价

PA6053

Rabbit Anti-Human CD3E pAb

Human

Rabbit

WB, IHC

50ul, 100ul

询价

PA6055

Rabbit Anti-Human CD3E pAb

Human

Rabbit

WB, IHC, IF

50ul, 100ul

询价

PA9777

Rabbit Anti-Human CD3EAP pAb

Human

Rabbit

WB

50ul, 100ul

询价

PA11011

Rabbit Anti-Human CD3E pAb

Human

Rabbit

WB, IHC, IP

50ul, 100ul

询价

MA500

Rabbit Anti-Human CD3E mAb

Human

Rabbit

WB, IHC

50ul, 100ul

询价

MA736

Rabbit Anti-Human CD3(epsilon+gamma)/CD3E+CD3G mAb

Human

Rabbit

WB, ELISA, FC

50ul, 100ul

询价

 

卡梅德其他优势产品:

 

重组蛋白

病毒蛋白

细菌蛋白